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Mechanistically, we found that the early pro-ferroptotic effect of dexamethasone, mediated through system Xcdependent impairment of GSH biosynthesis [7], was subsequently overridden by reduced iron availability at later time points

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Pharmacol Ther 123:386400 Lo M, Wang YZ, Gout PW (2008) The x(c) cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases

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